CALM-Brain initiative
News –
- Launched in Bengaluru, CALM-Brain is India’s first digital repository for major psychiatric disorders, including addiction, bipolar disorder, dementia, OCD, and schizophrenia.
- It compiles multi-modal data (clinical, imaging, behavioral, and genetic) from over 2,000 participants to improve diagnostic accuracy and personalize treatments.
CALM-Brain initiative:
- Developers: The project was developed by the Rohini Nilekani Centre for Brain and Mind (CBM), a partnership between NIMHANS and the National Centre for Biological Sciences (NCBS).
- Objectives: The repository aims to identify biomarkers, understand disease progression, and aid in personalized, data-driven treatment strategies.
Additional Information –
- Bipolar Disorder: Characterized by alternating periods of depression and mania (elevated mood, high energy, reckless behavior).
- Dementia: A neurodegenerative condition leading to cognitive decline, including memory loss and impaired thinking, with Alzheimer’s being the most common type. Studies show bipolar disorder and schizophrenia increase the risk of developing dementia.
- OCD (Obsessive Compulsive Disorder): Involves persistent, unwanted thoughts (obsessions) and repetitive behaviors (compulsions). It is often comorbid (occurring together) with schizophrenia and bipolar disorder.
- Schizophrenia: A severe, chronic mental disorder characterized by distortions in thinking, perception, emotions, language, and sense of self (hallucinations, delusions)







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